SS-31

SS-31, also known as elamipretide, is a synthetic tetrapeptide studied for its interaction with mitochondrial membranes. A&A Wellness supplies it as a lyophilized powder in 10mg and 50mg vials.

Two formats. The 10mg vial suits smaller studies, while the 50mg vial provides more material in one container.

Built on clarity. Specifications and storage conventions appear below.

Where it fits. SS-31 belongs to our mitochondria-focused research group with MOTS-c, and it is frequently discussed alongside NAD+ in mitochondrial biology.

SS-31 is sold for laboratory research only. It is not a drug, food, cosmetic or dietary supplement and is not for human or veterinary use.

Classification. SS-31 is one of the Szeto-Schiller (SS) peptides, a family of small, cell-permeable peptides. Its sequence is D-Arg-Dmt-Lys-Phe-NH2, where Dmt is 2',6'-dimethyltyrosine. It is described in the literature as associating with cardiolipin, a phospholipid concentrated in the inner mitochondrial membrane.

How it has been studied. SS-31 has been examined in cell-culture and animal models focused on mitochondrial structure and bioenergetics. Under the name elamipretide, it has also been evaluated in company-sponsored clinical development programs, with results published in peer-reviewed journals.

Regulatory status. Elamipretide has been the subject of FDA regulatory review as a pharmaceutical candidate. The A&A Wellness product is not a pharmaceutical product; it is a research material intended for laboratory use only and not for human use.

Why structure matters here. The alternating aromatic and basic residues in SS-31 are described as allowing it to cross cell membranes and concentrate at the inner mitochondrial membrane, which is why it is used as a tool in mitochondrial research.

Read SS-31: Research Overview for a referenced summary, and see MOTS-c for another mitochondria-focused compound.

Sealed and cold. Store lyophilized SS-31 sealed, dry and away from light. Freezing is the common convention for longer-term storage.

Avoid moisture. Allow cold vials to warm to room temperature before opening to limit condensation inside the vial.

Prepared solutions. Refrigerate and label reconstituted material. General practices are covered in the Peptide Storage Guide.