MOTS-c

MOTS-c is a short peptide first identified as being encoded within mitochondrial DNA. A&A Wellness supplies it as a lyophilized powder in 20mg and 40mg vials.

Two strengths. Choose a 20mg vial for smaller projects or a 40mg vial when you need more material from a single container.

Transparent details. Specifications and storage conventions are listed below.

Where it fits. MOTS-c belongs to our mitochondria-focused research group with SS-31, and it is often studied alongside the coenzyme NAD+.

MOTS-c is sold for laboratory research only. It is not a drug, food, cosmetic or dietary supplement and is not for human or veterinary use.

Classification. MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a 16-amino-acid peptide. It belongs to a group researchers call mitochondrial-derived peptides, which are encoded by short open reading frames within the mitochondrial genome.

How it has been studied. MOTS-c was described in the scientific literature in 2015, and research since then has examined it primarily in cell-culture and animal models. Studies have explored how it relates to cellular metabolic signaling and how its expression changes under different experimental conditions. Human data remain limited, and much of the published work is early-stage.

Regulatory status. MOTS-c is not approved by the FDA for any use. The A&A Wellness product is a research material intended for laboratory use only.

Why it drew attention. Most known peptides are encoded in nuclear DNA. The identification of a functional peptide encoded within the mitochondrial genome prompted new research into how mitochondria may communicate with the rest of the cell.

For a referenced overview, read MOTS-c: Research Overview. Researchers interested in mitochondria-focused compounds may also review SS-31 and NAD+.

Storage conventions. Keep lyophilized MOTS-c sealed, cold and protected from light and humidity. Freezing is typical for longer-term storage.

Handling. Let vials reach room temperature before opening, and avoid repeated freeze-thaw cycles.

After reconstitution. Refrigerate reconstituted material and label it clearly with contents and date. More in the Peptide Storage Guide.